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Zovirax (Acyclovir) is an antiviral medication. It works by stopping viral replication. However, Zovirax does not eliminate the virus, is not a cure, and does not prevent transmission to others.

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Uses

Acyclovir (ay-SYE-kloe-vir) is used in the treatment and suppression of genital herpes, shingles, chicken pox, and cold sores.

How to take

Take this medication as directed, with dosing times spaced evenly throughout the day. This medication can be taken with or without food. Acyclovir is best taken with a full glass of water. Drinking extra fluids while you are taking Acyclovir is recommended. For suppressive therapy, Acyclovir works best if it is taken at the same times each day.

Side effects

Common side effects include nausea, vomiting, general body discomfort, headache and diarrhea. These symptoms usually disappear as your body adjusts to the medication. Other common side effects include loss of appetite and headache. If these symptoms persist, please tell your doctor. Rare side effects include: numbness or tingling of the hands or feet; leg pain, sore throat, skin rash, dizziness or weakness. Seek medical attention right away if any of these severe side effects occur: Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); aggressive behavior, blood in the urine, confusion, decreased consciousness, decreased urination, hallucinations, mental or mood changes; red, swollen, blistered, or peeling skin; seizures, unusual bruising or bleeding.

Precaution

Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you: If you are pregnant, planning to become pregnant, or are breast-feeding; If you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement; If you have allergies to medicines, foods, or other substances; If you have kidney problems or a weakened immune system. Start therapy with Acyclovir at the earliest sign or symptom of shingles or genital herpes (pain, burning, blisters). If treating an acute outbreak, continue using Acyclovir for the full course of treatment even if you feel better in a few days. Acyclovir may cause drowsiness, dizziness, vision changes, or lightheadedness. These effects may be worse if you take it with alcohol or certain medicines. Use Acyclovir with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it. Acyclovir may cause dizziness, lightheadedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects. Acyclovir may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Acyclovir. Use a sunscreen or wear protective clothing if you must be outside for more than a short time. Acyclovir is not a cure for genital herpes and will not prevent the virus from spreading. Avoid sexual intercourse when sores are present to prevent infecting your partner. You can also be contagious and spread the herpes virus but not have any signs or symptoms at all. This is called asymptomatic viral shedding. Lab tests, including kidney function and serum urea nitrogen (BUN), may be performed while you use Acyclovir. These tests may be used to monitor your condition or check for side effects. Use Acyclovir with caution in the elderly; they may be more sensitive to its effects, especially confusion, drowsiness, or hallucinations. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Acyclovir while you are pregnant. Acyclovir is found in breast milk. If you are or will be breast-feeding while you use Acyclovir, check with your doctor. Discuss any possible risks to your baby.

Drug interactions

Tell your health care provider if you are taking any other medicines, especially any of the following: Medicines that may harm the kidney (eg, aminoglycoside antibiotics [eg, gentamicin], amphotericin B, cyclosporine, nonsteroidal anti-inflammatory drugs [NSAIDs] [eg, ibuprofen], tacrolimus, vancomycin) because the risk of kidney side effects may be increased. Ask your doctor if you are unsure if any of your medicines might harm the kidney. This may not be a complete list of all interactions that may occur. Ask your health care provider if Acyclovir may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

Missed dose

If you forget to take a dose of Acyclovir, do not double the dose, but take it as soon as you remember. If it is almost time for the next dose, however, skip the missed dose and resume your regular dosing schedule.

Storage

Store Acyclovir at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Acyclovir out of the reach of children and away from pets.

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